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A549 cells contain enlarged mitochondria with independently functional clustered mtDNA nucleoids

Mitochondria are commonly viewed as highly elongated organelles with regularly spaced mtDNA genomes organized as compact nucleoids that generate the local transcripts essential for production of mitochondrial ribosomes and key components of the respiratory chain. In contrast, A549 human lung carcino...

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Detalles Bibliográficos
Autores principales: Nasonovs, Aleksandrs, Garcia-Diaz, Miguel, Bogenhagen, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993880/
https://www.ncbi.nlm.nih.gov/pubmed/33765066
http://dx.doi.org/10.1371/journal.pone.0249047