Parameters and determinants of responses to selection in antibody libraries

The sequences of antibodies from a given repertoire are highly diverse at few sites located on the surface of a genome-encoded larger scaffold. The scaffold is often considered to play a lesser role than highly diverse, non-genome-encoded sites in controlling binding affinity and specificity. To gau...

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Detalles Bibliográficos
Autores principales: Schulz, Steven, Boyer, Sébastien, Smerlak, Matteo, Cocco, Simona, Monasson, Rémi, Nizak, Clément, Rivoire, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993935/
https://www.ncbi.nlm.nih.gov/pubmed/33765014
http://dx.doi.org/10.1371/journal.pcbi.1008751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993935/
https://www.ncbi.nlm.nih.gov/pubmed/33765014
http://dx.doi.org/10.1371/journal.pcbi.1008751

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