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A spinoparabrachial circuit defined by Tacr1 expression drives pain

Painful stimuli evoke a mixture of sensations, negative emotions and behaviors. These myriad effects are thought to be produced by parallel ascending circuits working in combination. Here, we describe a pathway from spinal cord to brain for ongoing pain. Activation of a subset of spinal neurons expr...

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Detalles Bibliográficos
Autores principales: Barik, Arnab, Sathyamurthy, Anupama, Thompson, James, Seltzer, Mathew, Levine, Ariel, Chesler, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993995/
https://www.ncbi.nlm.nih.gov/pubmed/33591273
http://dx.doi.org/10.7554/eLife.61135