Reprogramming of translation in yeast cells impaired for ribosome recycling favors short, efficiently translated mRNAs

In eukaryotes, 43S preinitiation complex (PIC) formation is a rate-determining step of translation. Ribosome recycling following translation termination produces free 40S subunits for re-assembly of 43S PICs. Yeast mutants lacking orthologs of mammalian eIF2D (Tma64), and either MCT-1 (Tma20) or DEN...

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Detalles Bibliográficos
Autores principales: Gaikwad, Swati, Ghobakhlou, Fardin, Young, David J, Visweswaraiah, Jyothsna, Zhang, Hongen, Hinnebusch, Alan G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993997/
https://www.ncbi.nlm.nih.gov/pubmed/33764298
http://dx.doi.org/10.7554/eLife.64283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993997/
https://www.ncbi.nlm.nih.gov/pubmed/33764298
http://dx.doi.org/10.7554/eLife.64283

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