Prenatal methadone exposure disrupts behavioral development and alters motor neuron intrinsic properties and local circuitry

Despite the rising prevalence of methadone treatment in pregnant women with opioid use disorder, the effects of methadone on neurobehavioral development remain unclear. We developed a translational mouse model of prenatal methadone exposure (PME) that resembles the typical pattern of opioid use by p...

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Detalles Bibliográficos
Autores principales: Grecco, Gregory G, Mork, Briana E, Huang, Jui-Yen, Metzger, Corinne E, Haggerty, David L, Reeves, Kaitlin C, Gao, Yong, Hoffman, Hunter, Katner, Simon N, Masters, Andrea R, Morris, Cameron W, Newell, Erin A, Engleman, Eric A, Baucum, Anthony J, Kim, Jiuen, Yamamoto, Bryan K, Allen, Matthew R, Wu, Yu-Chien, Lu, Hui-Chen, Sheets, Patrick L, Atwood, Brady K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993998/
https://www.ncbi.nlm.nih.gov/pubmed/33724184
http://dx.doi.org/10.7554/eLife.66230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993998/
https://www.ncbi.nlm.nih.gov/pubmed/33724184
http://dx.doi.org/10.7554/eLife.66230

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