HuR up-regulates cell surface PD-L1 via stabilizing CMTM6 transcript in cancer

Despite the well-established role of CMTM6 in the stabilization of cell surface PD-L1 in cancer cells, the mechanisms underlying CMTM6 expression and regulation are still largely unknown. Here we unexpectedly find a strikingly positive correlation between CMTM6 and Hu-Antigen R (HuR) expression in m...

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Detalles Bibliográficos
Autores principales: Liu, Yanbin, Li, Xingzhi, Zhang, Hui, Zhang, Mingming, Wei, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994200/
https://www.ncbi.nlm.nih.gov/pubmed/33649535
http://dx.doi.org/10.1038/s41388-021-01689-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994200/
https://www.ncbi.nlm.nih.gov/pubmed/33649535
http://dx.doi.org/10.1038/s41388-021-01689-6

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