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Lymph node metastasis-derived gastric cancer cells educate bone marrow-derived mesenchymal stem cells via YAP signaling activation by exosomal Wnt5a

Lymph node metastasis (LNM), a common metastatic gastric-cancer (GC) route, is closely related to poor prognosis in GC patients. Bone marrow-derived mesenchymal stem cells (BM-MSCs) preferentially engraft at metastatic lesions. Whether BM-MSCs are specifically reprogrammed by LNM-derived GC cells (L...

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Detalles Bibliográficos
Autores principales: Wang, Mei, Zhao, Xinxin, Qiu, Rong, Gong, Zheng, Huang, Feng, Yu, Wanjun, Shen, Bo, Sha, Xin, Dong, Haibo, Huang, Jiaying, Wang, Lin, Zhu, Wei, Xu, Wenrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994201/
https://www.ncbi.nlm.nih.gov/pubmed/33654199
http://dx.doi.org/10.1038/s41388-021-01722-8