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IL-17B/IL-17RB signaling cascade contributes to self-renewal and tumorigenesis of cancer stem cells by regulating Beclin-1 ubiquitination

Cancer stem cells (CSCs) are characterized by robust self-renewal and tumorigenesis and are responsible for metastasis, drug resistance, and angiogenesis. However, the molecular mechanisms for the regulation of CSC homeostasis are incompletely understood. This study demonstrated that the interleukin...

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Detalles Bibliográficos
Autores principales: Bie, Qingli, Song, Hui, Chen, Xinke, Yang, Xiao, Shi, Shuo, Zhang, Lihua, Zhao, Rou, Wei, Li, Zhang, Baogui, Xiong, Huabao, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994204/
https://www.ncbi.nlm.nih.gov/pubmed/33649532
http://dx.doi.org/10.1038/s41388-021-01699-4