Which Analysis Approach Is Adequate to Leverage Clinical Microdialysis Data? A Quantitative Comparison to Investigate Exposure and Response Exemplified by Levofloxacin

PURPOSE: Systematic comparison of analysis methods of clinical microdialysis data for impact on target-site drug exposure and response. METHODS: 39 individuals received a 500 mg levofloxacin short-term infusion followed by 24-h dense sampling in plasma and microdialysate collection in interstitial s...

Descripción completa

Detalles Bibliográficos
Autores principales: Busse, David, Schaeftlein, André, Solms, Alexander, Ilia, Luis, Michelet, Robin, Zeitlinger, Markus, Huisinga, Wilhelm, Kloft, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994214/
https://www.ncbi.nlm.nih.gov/pubmed/33723793
http://dx.doi.org/10.1007/s11095-021-02994-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994214/
https://www.ncbi.nlm.nih.gov/pubmed/33723793
http://dx.doi.org/10.1007/s11095-021-02994-1

Ejemplares similares