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Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes

Microglia, brain-resident macrophages, require instruction from the CNS microenvironment to maintain their identity and morphology and regulate inflammatory responses, although what mediates this is unclear. Here, we show that neurons and astrocytes cooperate to promote microglial ramification, indu...

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Detalles Bibliográficos
Autores principales: Baxter, Paul S., Dando, Owen, Emelianova, Katie, He, Xin, McKay, Sean, Hardingham, Giles E., Qiu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994374/
https://www.ncbi.nlm.nih.gov/pubmed/33761343
http://dx.doi.org/10.1016/j.celrep.2021.108882