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Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes
Microglia, brain-resident macrophages, require instruction from the CNS microenvironment to maintain their identity and morphology and regulate inflammatory responses, although what mediates this is unclear. Here, we show that neurons and astrocytes cooperate to promote microglial ramification, indu...
Autores principales: | Baxter, Paul S., Dando, Owen, Emelianova, Katie, He, Xin, McKay, Sean, Hardingham, Giles E., Qiu, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994374/ https://www.ncbi.nlm.nih.gov/pubmed/33761343 http://dx.doi.org/10.1016/j.celrep.2021.108882 |
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