Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice

Jak3 is the only non-promiscuous member of the Jak family of secondary messengers. Studies to date have focused on understanding and targeting the cell-autonomous role of Jak3 in immunity, while functional Jak3 expression outside the hematopoietic system remains largely unreported. We show that Jak3...

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Detalles Bibliográficos
Autores principales: Barcia Durán, José Gabriel, Lu, Tyler, Houghton, Sean, Geng, Fuqiang, Schreiner, Ryan, Xiang, Jenny, Rafii, Shahin, Redmond, David, Lis, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994450/
https://www.ncbi.nlm.nih.gov/pubmed/33767339
http://dx.doi.org/10.1038/s42003-021-01846-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994450/
https://www.ncbi.nlm.nih.gov/pubmed/33767339
http://dx.doi.org/10.1038/s42003-021-01846-3

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