IL-1β mediated nanoscale surface clustering of integrin α5β1 regulates the adhesion of mesenchymal stem cells

Clinical use of human mesenchymal stem cells (hMSCs) is limited due to their rapid clearance, reducing their therapeutic efficacy. The inflammatory cytokine IL-1β activates hMSCs and is known to enhance their engraftment. Consequently, understanding the molecular mechanism of this inflammation-trigg...

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Detalles Bibliográficos
Autores principales: Maynard, Stephanie A., Pchelintseva, Ekaterina, Zwi-Dantsis, Limor, Nagelkerke, Anika, Gopal, Sahana, Korchev, Yuri E., Shevchuk, Andrew, Stevens, Molly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994456/
https://www.ncbi.nlm.nih.gov/pubmed/33767269
http://dx.doi.org/10.1038/s41598-021-86315-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994456/
https://www.ncbi.nlm.nih.gov/pubmed/33767269
http://dx.doi.org/10.1038/s41598-021-86315-x

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