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Numaswitch: an efficient high-titer expression platform to produce peptides and small proteins

The production of peptides as active pharmaceutical ingredients (APIs) by recombinant technologies is of emerging interest. A reliable production platform, however, is still missing due the inherent characteristics of peptides such as proteolytic sensitivity, aggregation and cytotoxicity. We have de...

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Detalles Bibliográficos
Autores principales: Nguyen, Bach-Ngan, Tieves, Florian, Rohr, Thomas, Wobst, Hilke, Schöpf, Felix S., Solano, Jóse D. Montoya, Schneider, Julia, Stock, Janpeter, Uhde, Andreas, Kalthoff, Thomas, Jaeger, Karl Erich, Schmitt, Lutz, Schwarz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994495/
https://www.ncbi.nlm.nih.gov/pubmed/33765268
http://dx.doi.org/10.1186/s13568-021-01204-w