Enrichment of plasmid pool from E. coli for mass sequencing to detect untargeted mutagenic events

Translesion synthesis (TLS) is an event to cope with DNA damages. During TLS, the responsible TLS polymerase frequently elicits untargeted mutagenesis as potentially a source of genetic diversity. Identifying such untargeted mutations in vivo is challenging due to the bulk of DNA that does not under...

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Detalles Bibliográficos
Autores principales: Isogawa, Asako, Fuchs, Robert P., Fujii, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994540/
https://www.ncbi.nlm.nih.gov/pubmed/33786464
http://dx.doi.org/10.1016/j.xpro.2021.100399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994540/
https://www.ncbi.nlm.nih.gov/pubmed/33786464
http://dx.doi.org/10.1016/j.xpro.2021.100399

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