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Enrichment of plasmid pool from E. coli for mass sequencing to detect untargeted mutagenic events
Translesion synthesis (TLS) is an event to cope with DNA damages. During TLS, the responsible TLS polymerase frequently elicits untargeted mutagenesis as potentially a source of genetic diversity. Identifying such untargeted mutations in vivo is challenging due to the bulk of DNA that does not under...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994540/ https://www.ncbi.nlm.nih.gov/pubmed/33786464 http://dx.doi.org/10.1016/j.xpro.2021.100399 |