Design of buried charged networks in artificial proteins

Soluble proteins are universally packed with a hydrophobic core and a polar surface that drive the protein folding process. Yet charged networks within the central protein core are often indispensable for the biological function. Here, we show that natural buried ion-pairs are stabilised by amphiphi...

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Detalles Bibliográficos
Autores principales: Baumgart, Mona, Röpke, Michael, Mühlbauer, Max E., Asami, Sam, Mader, Sophie L., Fredriksson, Kai, Groll, Michael, Gamiz-Hernandez, Ana P., Kaila, Ville R. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994573/
https://www.ncbi.nlm.nih.gov/pubmed/33767131
http://dx.doi.org/10.1038/s41467-021-21909-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994573/
https://www.ncbi.nlm.nih.gov/pubmed/33767131
http://dx.doi.org/10.1038/s41467-021-21909-7

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