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Antibodies to Low-Copy Number RBC Alloantigen Convert a Tolerogenic Stimulus to an Immunogenic Stimulus in Mice

Red blood cells expressing alloantigens are well known to be capable of inducing robust humoral alloantibody responses both in transfusion and pregnancy. However, the majority of transfusion recipients and pregnant women never make alloantibodies, even after repeat exposure to foreign RBCs. More rec...

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Detalles Bibliográficos
Autores principales: Jash, Arijita, Usaneerungrueng, Chomkan, Howie, Heather L., Qiu, Annie, Luckey, Chance John, Zimring, James C., Hudson, Krystalyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994621/
https://www.ncbi.nlm.nih.gov/pubmed/33777014
http://dx.doi.org/10.3389/fimmu.2021.629608