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Trivial and nontrivial error sources account for misidentification of protein partners in mutual information approaches
The problem of finding the correct set of partners for a given pair of interacting protein families based on multi-sequence alignments (MSAs) has received great attention over the years. Recently, the native contacts of two interacting proteins were shown to store the strongest mutual information (M...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994710/ https://www.ncbi.nlm.nih.gov/pubmed/33767294 http://dx.doi.org/10.1038/s41598-021-86455-0 |