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Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease

Ulcerative colitis and Crohn’s disease are forms of inflammatory bowel disease whose incidence and prevalence are increasing worldwide. These diseases lead to chronic inflammation of the gastrointestinal tract as a result of an abnormal response of the immune system. Recent studies positioned Cortis...

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Detalles Bibliográficos
Autores principales: Rol, Álvaro, Todorovski, Toni, Martin-Malpartida, Pau, Escolà, Anna, Gonzalez-Rey, Elena, Aragón, Eric, Verdaguer, Xavier, Vallès-Miret, Mariona, Farrera-Sinfreu, Josep, Puig, Eduard, Fernández-Carneado, Jimena, Ponsati, Berta, Delgado, Mario, Riera, Antoni, Macias, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994712/
https://www.ncbi.nlm.nih.gov/pubmed/33767180
http://dx.doi.org/10.1038/s41467-021-22076-5