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Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease
Ulcerative colitis and Crohn’s disease are forms of inflammatory bowel disease whose incidence and prevalence are increasing worldwide. These diseases lead to chronic inflammation of the gastrointestinal tract as a result of an abnormal response of the immune system. Recent studies positioned Cortis...
Autores principales: | Rol, Álvaro, Todorovski, Toni, Martin-Malpartida, Pau, Escolà, Anna, Gonzalez-Rey, Elena, Aragón, Eric, Verdaguer, Xavier, Vallès-Miret, Mariona, Farrera-Sinfreu, Josep, Puig, Eduard, Fernández-Carneado, Jimena, Ponsati, Berta, Delgado, Mario, Riera, Antoni, Macias, Maria J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994712/ https://www.ncbi.nlm.nih.gov/pubmed/33767180 http://dx.doi.org/10.1038/s41467-021-22076-5 |
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