ATR activation is regulated by dimerization of ATR activating proteins

The checkpoint kinase ATR regulates DNA repair, cell cycle progression, and other DNA damage and replication stress responses. ATR signaling is stimulated by an ATR activating protein, and in metazoan cells, there are at least two ATR activators: TOPBP1 and ETAA1. Current evidence indicates TOPBP1 a...

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Detalles Bibliográficos
Autores principales: Thada, Vaughn, Cortez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994790/
https://www.ncbi.nlm.nih.gov/pubmed/33636182
http://dx.doi.org/10.1016/j.jbc.2021.100455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994790/
https://www.ncbi.nlm.nih.gov/pubmed/33636182
http://dx.doi.org/10.1016/j.jbc.2021.100455

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