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SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition

Viruses hijack host cell metabolism to acquire the building blocks required for replication. Understanding how SARS-CoV-2 alters host cell metabolism may lead to potential treatments for COVID-19. Here we profile metabolic changes conferred by SARS-CoV-2 infection in kidney epithelial cells and lung...

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Detalles Bibliográficos
Autores principales: Mullen, Peter J., Garcia, Gustavo, Purkayastha, Arunima, Matulionis, Nedas, Schmid, Ernst W., Momcilovic, Milica, Sen, Chandani, Langerman, Justin, Ramaiah, Arunachalam, Shackelford, David B., Damoiseaux, Robert, French, Samuel W., Plath, Kathrin, Gomperts, Brigitte N., Arumugaswami, Vaithilingaraja, Christofk, Heather R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994801/
https://www.ncbi.nlm.nih.gov/pubmed/33767183
http://dx.doi.org/10.1038/s41467-021-22166-4