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Structure of the p53/RNA polymerase II assembly

The tumor suppressor p53 protein activates expression of a vast gene network in response to stress stimuli for cellular integrity. The molecular mechanism underlying how p53 targets RNA polymerase II (Pol II) to regulate transcription remains unclear. To elucidate the p53/Pol II interaction, we have...

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Detalles Bibliográficos
Autores principales: Liou, Shu-Hao, Singh, Sameer K., Singer, Robert H., Coleman, Robert A., Liu, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994806/
https://www.ncbi.nlm.nih.gov/pubmed/33767390
http://dx.doi.org/10.1038/s42003-021-01934-4