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Apico-basal cell compression regulates Lamin A/C levels in epithelial tissues

The levels of nuclear protein Lamin A/C are crucial for nuclear mechanotransduction. Lamin A/C levels are known to scale with tissue stiffness and extracellular matrix levels in mesenchymal tissues. But in epithelial tissues, where cells lack a strong interaction with the extracellular matrix, it is...

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Detalles Bibliográficos
Autores principales: Iyer, K. Venkatesan, Taubenberger, Anna, Zeidan, Salma Ahmed, Dye, Natalie A., Eaton, Suzanne, Jülicher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994818/
https://www.ncbi.nlm.nih.gov/pubmed/33767161
http://dx.doi.org/10.1038/s41467-021-22010-9