Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers

The formula of a standardized extract of Centella asiatica (ECa 233) was modified to improve its dissolution, with implications for pharmacokinetics and metabolomic profile. This study aimed to understand the resultant changes in disposition kinetics of ECa 233 and alterations to human metabolome af...

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Detalles Bibliográficos
Autores principales: Songvut, Phanit, Chariyavilaskul, Pajaree, Khemawoot, Phisit, Tansawat, Rossarin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994819/
https://www.ncbi.nlm.nih.gov/pubmed/33767223
http://dx.doi.org/10.1038/s41598-021-86267-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994819/
https://www.ncbi.nlm.nih.gov/pubmed/33767223
http://dx.doi.org/10.1038/s41598-021-86267-2

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