De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-γ mediated histidine starvation

Intracellular pathogens including Mycobacterium tuberculosis (Mtb) have evolved with strategies to uptake amino acids from host cells to fulfil their metabolic requirements. However, Mtb also possesses de novo biosynthesis pathways for all the amino acids. This raises a pertinent question- how does...

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Detalles Bibliográficos
Autores principales: Dwivedy, Abhisek, Ashraf, Anam, Jha, Bhavya, Kumar, Deepak, Agarwal, Nisheeth, Biswal, Bichitra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994828/
https://www.ncbi.nlm.nih.gov/pubmed/33767335
http://dx.doi.org/10.1038/s42003-021-01926-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994828/
https://www.ncbi.nlm.nih.gov/pubmed/33767335
http://dx.doi.org/10.1038/s42003-021-01926-4

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