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Cross-kingdom metabolic manipulation promotes Salmonella replication inside macrophages

Replication inside macrophages is crucial for systemic dissemination of Salmonella in hosts. In a Nature Communications article, Jiang et al. show that Salmonella stimulates glycolysis and represses serine synthesis in macrophages, leading to accumulation of host glycolytic intermediates that the ba...

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Detalles Bibliográficos
Autores principales: Pérez-Morales, Deyanira, Bustamante, Víctor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994845/
https://www.ncbi.nlm.nih.gov/pubmed/33767154
http://dx.doi.org/10.1038/s41467-021-22198-w