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Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
Prion diseases are distinguished by long pre-clinical incubation periods during which prions actively propagate in the brain and cause neurodegeneration. In the pre-clinical stage, we hypothesize that upon prion infection, transcriptional changes occur that can lead to early neurodegeneration. A lon...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994852/ https://www.ncbi.nlm.nih.gov/pubmed/33767334 http://dx.doi.org/10.1038/s42003-021-01868-x |