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The M. tuberculosis Rv1523 Methyltransferase Promotes Drug Resistance Through Methylation-Mediated Cell Wall Remodeling and Modulates Macrophages Immune Responses

The acquisition of antibiotics resistance is a major clinical challenge limiting the effective prevention and treatment of the deadliest human infectious disease tuberculosis. The molecular mechanisms by which initially Mycobacterium tuberculosis (M.tb) develop drug resistance remain poorly understo...

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Detalles Bibliográficos
Autores principales: Ali, Sabeeha, Ehtram, Aquib, Arora, Naresh, Manjunath, P., Roy, Deodutta, Ehtesham, Nasreen Z., Hasnain, Seyed E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994892/
https://www.ncbi.nlm.nih.gov/pubmed/33777836
http://dx.doi.org/10.3389/fcimb.2021.622487