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Induced Neurons for Disease Modeling and Repair: A Focus on Non-fibroblastic Cell Sources in Direct Reprogramming

Direct cellular reprogramming exhibits distinct advantages over reprogramming from an induced pluripotent stem cell intermediate. These include a reduced risk of tumorigenesis and the likely preservation of epigenetic data. In vitro direct reprogramming approaches primarily aim to model the pathophy...

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Detalles Bibliográficos
Autores principales: Kim, Kathryn M., Thaqi, Mentor, Peterson, Daniel A., Marr, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995206/
https://www.ncbi.nlm.nih.gov/pubmed/33777923
http://dx.doi.org/10.3389/fbioe.2021.658498