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Mutant glucocorticoid receptor binding elements on the interleukin-6 promoter regulate dexamethasone effects
BACKGROUND: Glucocorticoids (GCs) have been extensively used as essential modulators in clinical infectious and inflammatory diseases. The GC receptor (GR) is a transcription factor belonging to the nuclear receptor family that regulates anti-inflammatory processes and releases pro-inflammatory cyto...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995394/ https://www.ncbi.nlm.nih.gov/pubmed/33771121 http://dx.doi.org/10.1186/s12865-021-00413-z |