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Dopamine receptor DOP-1 engages a sleep pathway to modulate swimming in C. elegans

Animals require robust yet flexible programs to support locomotion. Here we report a pathway that connects the D1-like dopamine receptor DOP-1 with a sleep mechanism to modulate swimming in C. elegans. We show that DOP-1 plays a negative role in sustaining swimming behavior. By contrast, a pathway t...

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Detalles Bibliográficos
Autores principales: Xu, Ye, Zhang, Lin, Liu, Yan, Topalidou, Irini, Hassinan, Cera, Ailion, Michael, Zhao, Zhenqiang, Wang, Tan, Chen, Zhibin, Bai, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995527/
https://www.ncbi.nlm.nih.gov/pubmed/33796839
http://dx.doi.org/10.1016/j.isci.2021.102247