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H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner

BACKGROUND: Evidence of global heterochromatin decay and aberrant gene expression in models of physiological and premature ageing have long supported the “heterochromatin loss theory of ageing”, which proposes that ageing is aetiologically linked to, and accompanied by, a progressive, generalised lo...

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Detalles Bibliográficos
Autores principales: Guillermo, Abigail R. R., Chocian, Karolina, Gavriilidis, Gavriil, Vandamme, Julien, Salcini, Anna Elisabetta, Mellor, Jane, Woollard, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995591/
https://www.ncbi.nlm.nih.gov/pubmed/33766022
http://dx.doi.org/10.1186/s12915-021-00984-8