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H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner
BACKGROUND: Evidence of global heterochromatin decay and aberrant gene expression in models of physiological and premature ageing have long supported the “heterochromatin loss theory of ageing”, which proposes that ageing is aetiologically linked to, and accompanied by, a progressive, generalised lo...
Autores principales: | Guillermo, Abigail R. R., Chocian, Karolina, Gavriilidis, Gavriil, Vandamme, Julien, Salcini, Anna Elisabetta, Mellor, Jane, Woollard, Alison |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995591/ https://www.ncbi.nlm.nih.gov/pubmed/33766022 http://dx.doi.org/10.1186/s12915-021-00984-8 |
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