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ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation

The NLRP3 inflammasome is a multiprotein complex responsible for the maturation of precursor forms of interleukin (IL)-1β and IL-18 into active proinflammatory cytokines. Increasing evidence suggests that modulation of redox homeostasis contributes to the activation of the NLRP3 inflammasome. Howeve...

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Detalles Bibliográficos
Autores principales: Zhang, Tianli, Tsutsuki, Hiroyasu, Islam, Waliul, Ono, Katsuhiko, Takeda, Kohsuke, Akaike, Takaaki, Sawa, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995658/
https://www.ncbi.nlm.nih.gov/pubmed/33740502
http://dx.doi.org/10.1016/j.redox.2021.101930