Cargando…
ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation
The NLRP3 inflammasome is a multiprotein complex responsible for the maturation of precursor forms of interleukin (IL)-1β and IL-18 into active proinflammatory cytokines. Increasing evidence suggests that modulation of redox homeostasis contributes to the activation of the NLRP3 inflammasome. Howeve...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995658/ https://www.ncbi.nlm.nih.gov/pubmed/33740502 http://dx.doi.org/10.1016/j.redox.2021.101930 |