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ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation
The NLRP3 inflammasome is a multiprotein complex responsible for the maturation of precursor forms of interleukin (IL)-1β and IL-18 into active proinflammatory cytokines. Increasing evidence suggests that modulation of redox homeostasis contributes to the activation of the NLRP3 inflammasome. Howeve...
Autores principales: | Zhang, Tianli, Tsutsuki, Hiroyasu, Islam, Waliul, Ono, Katsuhiko, Takeda, Kohsuke, Akaike, Takaaki, Sawa, Tomohiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995658/ https://www.ncbi.nlm.nih.gov/pubmed/33740502 http://dx.doi.org/10.1016/j.redox.2021.101930 |
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