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mTOR‐mediated calcium transients affect cardiac function in ex vivo ischemia–reperfusion injury

The mechanistic target of rapamycin (mTOR) is a key mediator of energy metabolism, cell growth, and survival. While previous studies using transgenic mice with cardiac‐specific overexpression of mTOR (mTOR‐Tg) demonstrated the protective effects of cardiac mTOR against ischemia–reperfusion (I/R) inj...

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Detalles Bibliográficos
Autores principales: Shimada, Briana K., Yorichika, Naaiko, Higa, Jason K., Baba, Yuichi, Kobayashi, Motoi, Aoyagi, Toshinori, Suhara, Tomohiro, Matsui, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995667/
https://www.ncbi.nlm.nih.gov/pubmed/33769701
http://dx.doi.org/10.14814/phy2.14807