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A new algorithm to train hidden Markov models for biological sequences with partial labels
BACKGROUND: Hidden Markov models (HMM) are a powerful tool for analyzing biological sequences in a wide variety of applications, from profiling functional protein families to identifying functional domains. The standard method used for HMM training is either by maximum likelihood using counting when...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995745/ https://www.ncbi.nlm.nih.gov/pubmed/33771095 http://dx.doi.org/10.1186/s12859-021-04080-0 |