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The transcriptional trajectories of pluripotency and differentiation comprise genes with antithetical architecture and repetitive-element content

BACKGROUND: Extensive molecular differences exist between proliferative and differentiated cells. Here, we conduct a meta-analysis of publicly available transcriptomic datasets from preimplantation and differentiation stages examining the architectural properties and content of genes whose abundance...

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Detalles Bibliográficos
Autores principales: Telonis, Aristeidis G., Rigoutsos, Isidore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995781/
https://www.ncbi.nlm.nih.gov/pubmed/33765992
http://dx.doi.org/10.1186/s12915-020-00928-8