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Lipopolysaccharide- TLR-4 Axis regulates Osteoclastogenesis independent of RANKL/RANK signaling

BACKGROUND: Lipopolysaccharide (LPS) is an endotoxin and a vital component of gram-negative bacteria’s outer membrane. During gram-negative bacterial sepsis, LPS regulates osteoclast differentiation and activity, in addition to increasing inflammation. This study aimed to investigate how LPS regulat...

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Detalles Bibliográficos
Autores principales: AlQranei, Mohammed S., Senbanjo, Linda T., Aljohani, Hanan, Hamza, Therwa, Chellaiah, Meenakshi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995782/
https://www.ncbi.nlm.nih.gov/pubmed/33765924
http://dx.doi.org/10.1186/s12865-021-00409-9