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Toll-Like Receptor 4 Inhibits Estradiol Secretion via NF-κB Signaling in Human Granulosa Cells

Toll-like receptor 4 (TLR4) may play a critical role in regulating follicular development. Data are scarce on the role of TLR4 in the follicle. This study investigated the effects of TLR4 on steroidogenesis in human granulosa cells. Immunohistochemical analysis revealed stage-specific expression of...

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Detalles Bibliográficos
Autores principales: Guan, Hai-Yun, Xia, He-Xia, Chen, Xiu-Ying, Wang, Lu, Tang, Zhi-Jing, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995891/
https://www.ncbi.nlm.nih.gov/pubmed/33776924
http://dx.doi.org/10.3389/fendo.2021.629554