Immunization with SP_1992 (DiiA) Protein of Streptococcus pneumoniae Reduces Nasopharyngeal Colonization and Protects against Invasive Disease in Mice

Knowledge-based vaccinology can reveal uncharacterized antigen candidates for a new generation of protein-based anti-pneumococcal vaccines. DiiA, encoded by the sp_1992 locus, is a surface protein containing either one or two repeats of a 37mer N-terminal motif that exhibits low interstrain variabil...

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Detalles Bibliográficos
Autores principales: Martín-Galiano, Antonio J., Escolano-Martínez, María S., Corsini, Bruno, de la Campa, Adela G., Yuste, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995960/
https://www.ncbi.nlm.nih.gov/pubmed/33668195
http://dx.doi.org/10.3390/vaccines9030187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995960/
https://www.ncbi.nlm.nih.gov/pubmed/33668195
http://dx.doi.org/10.3390/vaccines9030187

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