Development of a Sensitive Bioassay for the Analysis of IGF-Related Activation of AKT/mTOR Signaling in Biological Matrices

The bioactivity of the IGF system is not a function of isolated hormone concentrations in a given biological matrix. Instead, the biological activities of IGFs are regulated by IGFBPs, IGFBP proteases, and inhibitors of IGFBP proteases. Therefore, assays based on IGF-related bioactivity may describe...

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Detalles Bibliográficos
Autores principales: Walz, Michael, Höflich, Christine, Walz, Christina, Ohde, Daniela, Brenmoehl, Julia, Sawitzky, Mandy, Vernunft, Andreas, Zettl, Uwe K., Holtze, Susanne, Hildebrandt, Thomas B., Wolf, Eckhard, Hoeflich, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995968/
https://www.ncbi.nlm.nih.gov/pubmed/33668197
http://dx.doi.org/10.3390/cells10030482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995968/
https://www.ncbi.nlm.nih.gov/pubmed/33668197
http://dx.doi.org/10.3390/cells10030482

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