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Connexin therapeutics: blocking connexin hemichannel pores is distinct from blocking pannexin channels or gap junctions
Compounds that block the function of connexin and pannexin protein channels have been suggested to be valuable therapeutics for a range of diseases. Some of these compounds are now in clinical trials, but for many of them, the literature is inconclusive about the molecular effect on the tissue, desp...
Autores principales: | Acosta, Monica L., Mat Nor, Mohd N., Guo, Cindy X., Mugisho, Odunayo O., Coutinho, Frazer P., Rupenthal, Ilva D., Green, Colin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996017/ https://www.ncbi.nlm.nih.gov/pubmed/32985469 http://dx.doi.org/10.4103/1673-5374.290097 |
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