De Novo Synthesis of Phosphatidylcholine Is Essential for the Promastigote But Not Amastigote Stage in Leishmania major

Phosphatidylcholine (PC) is the most abundant type of phospholipids in eukaryotes constituting ~30% of total lipids in Leishmania. PC synthesis mainly occurs via the choline branch of the Kennedy pathway (choline ⇒ choline-phosphate ⇒ CDP-choline ⇒ PC) and the N-methylation of phosphatidylethanolami...

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Detalles Bibliográficos
Autores principales: Moitra, Samrat, Basu, Somrita, Pawlowic, Mattie, Hsu, Fong-fu, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996062/
https://www.ncbi.nlm.nih.gov/pubmed/33777852
http://dx.doi.org/10.3389/fcimb.2021.647870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996062/
https://www.ncbi.nlm.nih.gov/pubmed/33777852
http://dx.doi.org/10.3389/fcimb.2021.647870

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