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Interaction of Trypanosoma cruzi Gp82 With Host Cell LAMP2 Induces Protein Kinase C Activation and Promotes Invasion

The surface molecule gp82 of metacyclic trypomastigote (MT) forms of Trypanosoma cruzi, the protozoan parasite that causes Chagas disease, mediates the host cell invasion, a process critical for the establishment of infection. Gp82 is known to bind to the target cell in a receptor-dependent manner,...

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Detalles Bibliográficos
Autores principales: Onofre, Thiago Souza, Rodrigues, João Paulo Ferreira, Shio, Marina Tiemi, Macedo, Silene, Juliano, Maria Aparecida, Yoshida, Nobuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996063/
https://www.ncbi.nlm.nih.gov/pubmed/33777840
http://dx.doi.org/10.3389/fcimb.2021.627888