Systems Biology Analysis of the Radiation-Attenuated Schistosome Vaccine Reveals a Role for Growth Factors in Protection and Hemostasis Inhibition in Parasite Survival

In spite of several decades of research, an effective vaccine against schistosomiasis remains elusive. The radiation-attenuated (RA) cercarial vaccine is still the best model eliciting high protection levels, although the immune mechanisms have not yet been fully characterized. In order to identify...

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Detalles Bibliográficos
Autores principales: Farias, Leonardo Paiva, Vitoriano-Souza, Juliana, Cardozo, Lucas Esteves, Gama, Leonardo Dos Reis, Singh, Youvika, Miyasato, Patrícia Aoki, Almeida, Giulliana Tessarin, Rodriguez, Dunia, Barbosa, Mayra Mara Ferrari, Fernandes, Rafaela Sachetto, Barbosa, Tereza Cristina, Neto, Almiro Pires da Silva, Nakano, Eliana, Ho, Paulo Lee, Verjovski-Almeida, Sergio, Nakaya, Helder Imoto, Wilson, Robert Alan, Leite, Luciana Cezar de Cerqueira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996093/
https://www.ncbi.nlm.nih.gov/pubmed/33777004
http://dx.doi.org/10.3389/fimmu.2021.624191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996093/
https://www.ncbi.nlm.nih.gov/pubmed/33777004
http://dx.doi.org/10.3389/fimmu.2021.624191

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