Sirt1 and Sirt3 Activation Improved Cardiac Function of Diabetic Rats via Modulation of Mitochondrial Function

In the present study, we aimed to evaluate the effect of Sirt1, Sirt3 and combined activation in high fructose diet-induced insulin resistance rat heart and assessed the cardiac function focusing on mitochondrial health and function. We administered the Sirt1 activator; SRT1720 (5 mg/kg, i.p.), Sirt...

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Detalles Bibliográficos
Autores principales: Paramesha, Bugga, Anwar, Mohammed Soheb, Meghwani, Himanshu, Maulik, Subir Kumar, Arava, Sudheer Kumar, Banerjee, Sanjay K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996143/
https://www.ncbi.nlm.nih.gov/pubmed/33668369
http://dx.doi.org/10.3390/antiox10030338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996143/
https://www.ncbi.nlm.nih.gov/pubmed/33668369
http://dx.doi.org/10.3390/antiox10030338

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