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A Robust Bioassay of the Human Bradykinin B(2) Receptor That Extends Molecular and Cellular Studies: The Isolated Umbilical Vein
Bradykinin (BK) has various physiological and pathological roles. Medicinal chemistry efforts targeted toward the widely expressed BK B(2) receptor (B(2)R), a G-protein-coupled receptor, were primarily aimed at developing antagonists. The only B(2)R antagonist in clinical use is the peptide icatiban...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996148/ https://www.ncbi.nlm.nih.gov/pubmed/33668382 http://dx.doi.org/10.3390/ph14030177 |